B.pharm notes topic- History of microbiology

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      -History of microbiology-

1. Antony van leeuwenhoek (1632-1723)

* Antony van leeuwenhoek (1677) could see them in simple (one lens) microscope.

* He discoverd major classes of bacteria ( spheres , rods and spirals ) , protozoa,algae , yeast , erythrocytes, spermatozoa and tha capillary circulation.

Spontaneous generation of organization-(abiogenesis);

*The theory of spontaneous generation states the the microbes arise automatically in decomposing organic matter.

Golden Era of microbiology (1860-1910);

* Golden Era of microbiology started with the work of Louis' Pasteur and Robert koch .

Louis' Pasteur (1822-1895)

*He investigated number of aspect such as he showed that boiled medium could remain  clear in a "swan-neck" flask. open to the air through a sinous horizontal tube  in which dust particle would settle as air re-entered the cooling vessel.

* Pasture (1857) became interested in the fermentation product and observed different kind of microbes associated with different kind of fermentation 
such as; Spheres of variable size in the alcoholic fermentation , smaller road ( lactobacilli) in the lactic fermentation during this experiment.

* Posteur developed the procedure of gentle heating (I.e ;Pasteurization)  to prevent the spoilage of beer and wine by  undesired microbes.

Germ theory of disease; 

* The germ theory of disease has presented a great stimulus in microbiology and medicine.

Edward jeener (1796);

*Introduction vaccination against small pox , using material from lesions of a similar disease of cattle (cowpox).

                

 

                                    Thankyou

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