Medicinal chemistry -1 ( Introduction,drug discovery, development )
*Medicinal chemistry* Introduction: • As defined by IUPAC medicinal chemistry is a chemistry based discipline involving aspects of the biological , medical and pharmaceutical sciences. * Medicinal chemistry is concerned all about to the designing of drug which cover 3 stages. • Discovery; Choice of therapeutic target, identification of lead. • Optimization; Optimization of pharmacodynamics and pharmacokinetics. • Development Stage ; Include preclinical and clinical studies. Drug development involves; • Potency of drug. • Preclinical trial ( initial biological and toxicological studies. • Design manufacturing process. • Clinical trials. • Ragistration and marketing of the drug.
